area 47s ( 47s )

The term area 47s refers to a narrow strip of orbital prefrontal cortex located caudally in the lateral orbital gyrus. Located in proximity to the lateral orbital sulcus (hence 's' in the acronym), it is bounded rostrally by area 47L and area 47m, laterally by area AAIC and area AVI, caudally by area Pir and area pOFC, and medially by area 13l. Defined in the human by multiple criteria, it is fMRI-activated in LANGUAGE-STORY, STORY-MATH, THEORY OF MIND-RANDOM, and FACES-SHAPES contrast tasks ( Glasser-2016 ). Its equivalent in the macaque is often referred to as area 12o. An identifying feature is a sparsity of myelination. Other features that distinguish it from some adjacent areas are a weakly stained internal granular layer (IV) and lack of sublamination of the internal pyramidal layer (V) ( Carmichael-1994 ). As granular prefrontal cortex, it has no architectonic equivalent in the the rat ( Wallis-2012 )..

Also known as

Name Language Source Source Citation Source Title Organism
area 47s English Glasser-2016 Nature. 2016 August 11; 536(7615): 171–178. doi:10.1038/nature18933. A multimodal parcellation of human cerebral cortex: human
47s acronym Glasser-2016 Nature. 2016 August 11; 536(7615): 171–178. doi:10.1038/nature18933. A multimodal parcellation of human cerebral cortex: human
area 47/12s English Ongur-2003 J Comp Neurol. 2003 Jun 2;460(3):425-49. Architectonic subdivision of the human orbital and medial prefrontal cortex human
47/12s acronym Ongur-2003 J Comp Neurol. 2003 Jun 2;460(3):425-49. Architectonic subdivision of the human orbital and medial prefrontal cortex human
area 12o English Carmichael-1994 Architectonic subdivision of the orbital and medial prefrontal cortex in the macaque monkey macaque
12o acronym Carmichael-1994 Architectonic subdivision of the orbital and medial prefrontal cortex in the macaque monkey macaque
area 12o (macaque) English NeuroNames University of Washington, Seattle, WA NeuroNames macaque
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